91免费永久在-91免费永久在线地址-91免费在-91免费在线-91免费在线观看-91免费在线观看视频-91免费在线看-91免费在线看片-91免费在线视-91免费在线视频

moda

Snug with your bugs? How microbes control your sleep

bodxlxwvy

19 Sep 2025(atualizado 19/09/2025 às 18h38)

The bacteria living in your guts and mouths could be controlling how you sleep at night. Now scienti

Temas

Compartilhe

Telefone sem fio' ajuda a prevenir desastres em Petr\u00f3polisSnug with your bugs? How microbes control your sleep

Snug with your bugs? How microbes control your sleep

The bingo de painsbacteria living in your guts and mouths could be controlling how you sleep at night. Now scientists want to use them to help you rest better.

As you lie in bed tonight, your body will be a teeming mass of activity. Across almost every inch of your body – and inside it too – billions of tiny organisms are writhing and jostling for space. But if that horrifying thought is likely to keep you up at night, consider this: they might also help you get a better night's sleep.

Emerging research suggests that the communities of bacteria, viruses and fungi that make up our body's microbiota can influence our sleep. Depending on the composition of our personal microbial ecosystem, the amount of shut eye we get can either improve or deteriorate.

And tantalisingly, it could offer new ways of tackling sleep-related conditions caused by a disrupted body clock, described by sleep scientists as circadian rhythms. While many people currently rely on sleeping pills to quell persistent insomnia, the future might see friendly bacteria deployed to help us nod off, and even address obstructive sleep apnoea, a condition in which people struggle to breathe normally while asleep. It would bring new meaning to the term "sleep hygiene".

"The predominant theory for a long time has been that having sleep disorders is disruptive to our microbiomes," says Jennifer Martin, a University of California Los Angeles professor and board member of the American Academy of Sleep Medicine. "But some of the evidence we're seeing now indicates that it's probably a relationship that goes in both directions."

In May, new research presented at an academic conference for sleep scientists summed up what a growing number of other studies are revealing. It found that teenagers and young adults with a greater diversity of microbes in their mouths tended to have a longer sleep duration.

Research has also shown that people with medically diagnosed insomnia have lower bacterial diversity in their guts compared to normal sleepers, something typically linked to a less healthy immune system and impairments in dealing with fats and sugars, which can lead to an increased risk of diabetes, obesity and heart disease. Another study, in which 40 people volunteered to wear sleep trackers for a month and have their gut microbiome analysed, also found that poor sleep quality correlated with a less diverse population of gut microbes.

Plus, people with social jetlag – where their sleep patterns during the working week and weekend vary enormously – had significantly different gut microbiomes to those whose sleep patterns did not vary much, according to data analysed by UK health-tech company Zoe.

"Circadian rhythm disruption occurs in people who stay up later and sleep in on the weekends, those who work long hours, like first responders, police and security, paramedics and the military, and in people who eat too close to bedtime," says Kenneth Wright, a professor of integrative physiology at the University of Colorado Boulder in the US. "This can cause gastrointestinal disturbances and metabolic diseases, which are common for example in shift workers, and a disturbed microbiome may play a role."

It's possible that individuals with disrupted sleep tend to follow less healthy diets, which then impacts their microbiome, suggests Sarah Berry, a nutritional sciences professor at King's College London and chief scientist at Zoe. She cites other research not conducted by Zoe that found that short sleepers tend to subconsciously increase their sugar intake.

"Part of the theory behind this is that when you've had a bad night's sleep, the reward centres in your brain are heightened the next day, and so you seek out that quick fix," she says. "Your brain is kind of tricking you into feeling, 'Ok, I need refined carbohydrates', to get that quick burst of energy."

But changing dietary patterns in response to sleep deprivation is not the whole story. Berry and her colleagues found nine species that were greater in abundance and eight that were less abundant in people with social jet lag compared to those without this variation in sleep patterns. But they found that diet appeared to only account for changes in abundance for four of these microbe species.

Jaime Tartar, a professor of psychology and neuroscience at Nova Southeastern University in Florida who was not involved in the Zoe study, says she has become increasingly convinced that certain microbes play a direct role in sleep. She cites Firmicutes, one of the most dominant taxonomic groups of bacteria found in the gut. In tests where Tartar and her colleagues monitored the sleep and tested the gut microbes of 40 men, they found 15 different groups of Firmicutes bacteria that correlated with a number of sleep metrics in varying ways. "We don't have all the answers right now, but it certainly seems that some can improve sleep and others can impair sleep," she says.

In some cases, sleep disruptions might actively drive shifts in these microbial populations through impairing the immune system and its ability to regulate microbes, which could in turn increase the likelihood of longer-term sleep problems.

But researchers including Tartar and Martin suggest that some sleep problems could also be initiated by microbial imbalances in the gut or mouth. They believe that certain bacteria may actively alter the quality of the sleep we get by shifting our circadian rhythms – the internal body clock that governs our sleep – and altering our food intake, which also impacts the kip we get.

Some evidence for this comes from a series of studies involving so-called faecal transplants. In one 2024 study, scientists transplanted faeces – along with the gut microbes it contained – from humans and implanted it into the intestines of mice. Rodents who received faeces from people suffering from jetlag and insomnia developed insomnia-like behaviours, becoming more awake during their typical sleeping hours. In another study where mice received a series of gut microbes from humans before, during, and after recovery from jetlag, the transplantation of microbes during the jetlag phase saw them gain weight and struggle to control their blood sugar.

A number of small-scale studies in humans by researchers in China have shown that faecal transplants could help to improve the sleep of patients suffering from chronic insomnia and sleep disorders. Of course, it's worth remembering that many aspects of sleep involve psychological factors, so it is possible that receiving a transplant led patients to change their mindset in a way that allowed them to sleep more soundly. A randomised, double-blind clinical trial will be needed to test the efficacy properly, the researchers say.

But there are other reasons to think it might work. Diet, for example, is well known to affect sleep. When a group of 15 healthy young men followed a high fat, high sugar diet for a week, this altered their brains' electrical patterns during deep sleep, although it's hard to draw firm conclusions from such a small sample size. Similarly, in an experiment where volunteers had their sleep assessed after receiving antibiotics, evidence suggested that this reduced the amount of non-rapid eye movement sleep, an essential part of the sleep cycle where our bodies undergo repairs and new memories and skills are reinforced, although the findings did not apply for all antibiotics, and once again, the study was small.

Changes in the balance of our gut microbes may also alter the amounts of useful chemicals they produce as they help to break down our food. This in turn can influence sleep quality, says Tartar.

We know, for example that some gut microbes produce neurotransmitters such as gamma-aminobutyric, dopamine, norepinephrine and serotonin, or short-chain fatty acids such as butyrate, all of which play a role in sleep. "While they're produced in the gut, they can influence [the] brain," says Tartar.

If those microbes decrease in abundance, then their chemical influence on the brain will likely also lessen while other microbes that use foods such as saturated fat and sugar to synthesise inflammatory molecules can proliferate. Some of these inflammatory chemicals, including certain bile acids, are thought to be capable of disrupting the brain's circadian rhythms.

Martin says the same is likely to be true of the oral microbiome. Heightened inflammation, caused by microbes flourishing in people who have poor diets or poor dental health, could raise those individuals' risk of issues including obstructive sleep apnoea, in which the walls of the throat relax during sleep, interrupting normal breathing.

"If the microbiome is unbalanced, that could lead to local and systemic inflammation that can cause narrowing of the airway, the release of stress hormones and a lot of things that are then disruptive to sleep down the line," says Martin. Narrowed or blocked airways can lead to obstructive sleep apnoea and snoring.

With all of this in mind, it's possible that probiotics (pills that administer a targeted bacterial strain) or prebiotics (non-digestible food ingredients that selectively feed beneficial gut bacteria) could help to treat certain sleep disturbances. Tartar points to one study that showed how a particular probiotic, the Lactobacillus casei strain Shirota, improved sleep compared to a placebo in a group of 94 medical students while they were going through a stressful period in the academic year.

Berry says that Zoe recently completed a six week trial involving 399 healthy UK adults in a project called the BIOME study. The research, which is still undergoing peer review, saw participants receive one of three foods. One group were given a "super fuel for the microbiome" – a prebiotic blend containing more than 30 different whole food ingredients from baobab fruit to lions mane. Another group received a daily probiotic in the form of the bacteria L. rhamnosus. The final group were given?bread croutons with the equivalent calories to the prebiotic blend as a control. Compared to the crouton group, a greater proportion of those receiving the prebiotic blend experienced improved sleep, although this was based on self-reports rather than objective measurements.

More like this:

? Seven ways to improve your sleep according to science

? How often should you change your bed sheets

? The forgotten medieval habit of 'two sleeps'

Martin, while intrigued by such results, emphasises the need for larger, more robust trials that compare prebiotic or probiotic interventions to existing treatments, which are already known to be effective for tackling sleep problems. That includes cognitive behavioural therapy (a type of talk therapy often reffered to as CBT) and various medications.

"I'm always cautious about suggesting that someone go spend $30 (£22) at a health food store on something that doesn't have proven effectiveness, when we know there are effective medical therapies out there," she says.

She expresses interest in finding out whether probiotics could help people with mild cases of obstructive sleep apnoea, possibly in combination with existing oral devices that reposition the jaw in order to help prevent breathing disturbances. Since 20-30% of people with chronic insomnia do not currently respond to cognitive behavioural therapy, Martin wonders if probiotics or prebiotics could help them.

"I would love to see studies like that," she says. "Clinically, we struggle with how to help that subset of patients, a lot of whom don't want to use a sedating medication."

But if microbiology does prove to have a verifiable impact on sleep quality, that could help all kinds of people.

"Circadian disruption is very common in society," says Wright. "It can occur with jetlag, certain careers and lifestyles and age-related diseases. There is the potential for many people to benefit."

It would certainly put a new spin on bed bugs.

--

If you liked this story,?sign up for The Essential List newsletter?– a handpicked selection of features, videos and can't-miss news, delivered to your inbox twice a week.

For more science, technology, environment and health stories from the BBC, follow us on?Facebook?and?Instagram.

Copyright 2025 BBC. All rights reserved. The BBC is not responsible for the content of external sites.?Read about our approach to external linking.

NEWSLETTER GRATUITA

Nexo | Hoje

Watch_Moment_police_device_breaks_off_fleeing_cars_rear_axle.txt

Embaixada de Portugal abre ao público exposi??o sobre os 50 anos da Revolu??o dos Cravos.txt lazer e os entretenimento entretenimento.

GRáFICOS

nos eixos

Turkey's 'tough guy’ president is accused of silencing opponents.txt

Entenda a disputa bilionária entre J&F e Paper Excellence pela Eldorado Versus Valor Econ?mico.txt enciclopédia e os moda entretenimento.

Navegue por temas

Ningu\u00e9m acreditava na gente', diz Cole Palmer Embaixada de Israel no Brasil decreta luto e lamenta morte de casal em atentado nos EUA.txt Empresas familiares e de capital fechado demandam uma experiência diferenciada para realizar auditorias Impacting the future Valor Econ?mico.txt Ningu\u00e9m acreditava na gente', diz Cole Palmer Endividamento cresce no Brasil; veja como organizar as finan?as Itaú Valor Econ?mico.txt S\u00f3 o Santos pode me proporcionar o carinho de que preciso', diz Neymar Encontro de queens! Galisteu, Tici Pinheiro e Rafa Brites posam juntas e divertem os f?s – Record.txt Em reuni?o do Brics, Lula diz que 'sem soberania digital, seremos vulneráveis à manipula??o estrangeira' Brasil Valor Econ?mico.txt Empresas se preparam para a próxima fase da revolu??o da IA Transforma??o nos negócios Valor Econ?mico.txt Embrapa desenvolve sistema que amplia produ??o de biogás a partir de resíduos da Ceasa-CE.txt
色偷偷AV亚洲男人的天堂 | 福利视频在线播放 | 色六月婷婷亚洲婷婷六月 | 黄色一级片在线观看 | 美女乱子伦高潮 | 一级毛片免费在线播放 | 双性男生被老师摁着调教 | 成人在线精品视频 | 国产一区电影 | 国产精品卡一卡2卡三卡网站 | 国产亚洲国产bv网站在线 | 亚洲H成年动漫在线观看不卡 | 好男人免费影院www神马 | 精品国产亚洲午夜精品AV | 午夜欧美性欧美 | 亚洲一区二区三区秋霞秋理 | 欧美真人性做爰一二区欧美影院 | 99热久久这里只精品国产WWW | 狠狠撸影视| 麻豆精品人妻一区二区三区蜜桃 | 国产视频1 | 自拍 偷拍 亚洲 经典 | 自拍视频一区二区 | 性欧美网站 | 国产精品热久久高潮AV袁孑怡 | 666西西人体做爰大胆图片 | 成人网页 | 国产又黄又刺激的A片小说 国产又黄又粗又爽又色的视频软件 | 好男人WWW神马社区在线观看 | 精品无人乱码一区二区三区的优势 | 国产一级大片免费看 | 国产无遮挡又黄又爽在线视频 | 日本aa视频| 在线观看你懂得 | 欧美乱妇日本无乱码特黄大片 | caoporn视频在线 | 成年私人影院网站在线看 | 日本高清免费不卡在线播放 | 免费jizz在线播放视频 | 免费国产黄网在线观看 | 国产69精品久久久久久人妻精品 | 日本中文字幕一区 | 欧美日韩不卡合集视频 | 日本视频免费在线观看 | 樱花草WWW在线视频播放 | 伊人在综合| 一本大道熟女人妻中文字幕在线 | 国产在线亚洲精品观看不卡 | 甜涩性爱下载 | 麻豆出品视频在线 | 一级毛片一级毛片一级毛片一级毛片 | 亚洲欧美国产日本 | 99视频在线看观免费 | 国产肥熟女老太老妇A片 | 日本性视频网站 | 亚洲乱码精品久久久久.. | 午夜影院a级片 | 把腿张开老子臊烂你多P视频 | 17C丨国产丨精品入口永久地址 | 55夜色66成年视频观看免费 | 麻豆传媒在线完整视频免费 | 国产在线2021 | 国产精品综合AV一区二区国产馆 | 嫩草国产露脸精品国产软件 | 精品欧美日韩一区二区三区 | 观看在线人成电影 | 伦理电影中文字幕韩国在线观看 | 美女解开胸衣露出奶头的游戏 | 日韩精品人妻AV一区二区三区 | 中文无码字慕在线观看 | 秋霞成人国产理论A片 | 欧美三级经典免费播放 | 偷拍亚洲网友图片区 | 日本一区二区免费看 | 国内露脸少妇精品视频 | 亚洲AV久久无码精品夜夜挺 | 国产精品成人四虎免费视频 | 伊思人在线| 国精产品一二二区视早餐有限 | 欧美色交| 天天躁日日2018躁狠狠躁 | 日韩美无码有码人妻精品 | 男人的天堂AV亚洲一区2区 | 久青草免费视频 | 欧美日韩福利视频 | 欧美无人区码卡二卡3卡2022 | 中文在线最新版天堂 | 六月丁香久久 | 黑人巨茎大战白人女40CMO | 色噜噜狠狠大色综合 | 大色网我爱看 | 天天搞天天色 | 日韩美女福利视频 | 欧美成人精品福利在线视频 | 伦理电影中文字幕韩国在线观看 | 乱公和我做爽死我视频 | 一区二区中文字幕在线观看 | 久久视频在线视频 | 一本久道久久综合中文字幕 | 国产区1| 最近免费中文字幕大全高清10 | 国产性生大片免费观看性 | avtom影院永久地址人人影院 | 九九九国产 | 日本在线不卡免费视频 | 免费观看欧美成人1314w色 | 日韩免费高清视频 | 少妇性L交大片W | 蜜臀AV久久国产午夜福利软件 | 蜜芽成人A片免费视频 | 中国精品久久精品三级 | 艳妇臀荡乳欲伦交换AV1 | 少妇人妻偷人精品无码视频新浪 | 美美哒免费高清影院在线观看8 | 第四色婷婷墓地 | 亚洲中字慕日产2024 | 国产剧情一卡二卡麻豆 | 在镜头里被CAO翻了H | 自拍自录videosfree自拍自录 | 无码人妻精品国产婷婷 | 日本亚洲欧洲色情 | 成人黄网18免费观看的网站 | 亚洲国产成人精品动漫 | 午夜亚洲国产理论片二级港台二级 | 久久无码AV亚洲精品色午夜麻豆 | 黄色网址免费在线 | 黄色免费网址在线观看 | 亚洲熟少妇在线播放999 | 精产国品一区二区三产区 | 第一次破處在线国语视频播放 | 久就热视频精品免费99 | 真人插B免费视频播放 | 免费污视频在线观看 | 在线观看的免费网站 | 久久视频在线观看精品 | 欧美精品高清在线xxxx | 色婷婷AV99XX | 十八禁啪漫动漫在线看 | 日本强伦姧熟睡人妻完整视频 | 波多野结衣 一区二区 | 天美MD豆传媒一二三区进 | 91在线视频一区 | 国产资源视频 | 女人张开腿让男人桶免费网站 | 女网址www女影院 | 亚洲国产精品久久综合 | 中文字幕乱码亚洲精品一区 | 欲妇荡岳丰满少妇A片24小时 | 除却巫山在线 | 日本黄页免费大片在线观看 | 美国黄色毛片一级 | 又黄又猛又爽大片免费 | 波多野结衣免费在线 | 美女露出尿口让男人揉动态图网站 | 欧美激情黄色片 | 影音先锋av悠悠资源网 | 精品国产3p一区二区三区 | chinese乱子伦xxxx视频播放 | 国产女人18毛片水真多 | 三级在线不卡 | 午夜小视频免费观看 | 成人午夜小视频 | 欧美国产日本高清不卡 | 亚洲精品成人无码A片在线 亚洲精品1卡2卡三卡4卡乱码 | 强被迫伦姧高潮无码A片漫画 | 国产精品视频在线观看 | 日韩啊v | 2024一級特黃色毛片免費看 | 院人全年无休计划2免费观看全集完整版 | 亚洲国产专区校园欧美 | 日韩精品专区在线影院重磅 | 华人91视频 | 国产精品99久久久久久AV小说 | 日韩二三区 | 一级一毛片a级毛片 | 久久尹人| 又大又黄又爽免费看A片 | 精品乱码一卡2卡三卡4卡网 | 久久国产精品无码视欧美 | a级片在线观看 | 日韩欧美视频一区 | 国内精品久久久久久中文字幕 | 18岁禁看网站 | 国产在线精品亚洲观看不卡欧美 | 国内精品久久久久久久久久久久 | 好紧好湿太硬了我太爽了文字 | 国产精品高潮呻吟久久影视A片 | 成人在线观看免费视频 | 黄色网址在线免费播放 | 国产成人精品久久久久婷婷 | 天天操天天射天天 | 中文字幕va一区二区三区 | 五月婷婷啪啪 | 最好看的最新的中文字幕3 最近2019中文字幕免费 | 美妇吞吐粗长撞击迎合 | 日本高清视频免费在线观看 | 欧美日韩亚洲综合2019 | 成人色网站大全 | 国产人妻无码一区二区三区18 | 天天天做天天天天爱天天想 | 国产乱码免费卡1卡二卡3卡四卡 | 久久视热在线视频精品 | 小泽玛利亚 bt | 精品成人 | 婷婷97狠狠的狠狠的爱 | 男女做爰猛烈啪啪吃奶动A 男人j进女人j的图片 | 阿娇艳Z门照片无码AV4I | YIN乱大合集未删节TXT下载 | 国内精品久久久久久久久 | 男人的天堂亚洲一线AV在线观看 | GOGO大胆国模一区二区私拍 | 亚洲中文字幕永久在线全国 | 久久久精品免费 | 公交车上荫蒂添的好舒服的电影 | 亚洲精品久久久久一区二区三区 | 大陆精品福利网址导航在线 | av我要看 | 亚洲永久精品日本无码 | 国产人澡人澡澡澡人碰视频 | 四虎影视免费完整版在线观看 | 久久综合影院 | 狠狠色噜噜狠狠狠狠狠色综合久久 | 国产成人精品曰本亚洲 | 男人天堂2024亚洲男人天堂 | www毛片com| 亚洲 欧美 中文 在线 视频 | 乱肉杂交怀孕系列小说BL | 国产亚洲精品久久久久苍井松 | 中文字幕国产视频 | 99精品久久久久久 | 波多野衣结在线精品二区 | 亚洲狠狠婷婷综合久久久久网站 | 欧美日韩亚洲中字二区 | 国产成人精品福利色多多 | 无遮挡国产高潮视频免费观看 | 成人精品视频99在线观看免费 | 亚洲免费黄网 | 999精品视频这里只有精品 | 欧美xxxx成人免费网站 | 日本韩国台湾香港三级 | 8x在线观看免费视频 | 2024国产大片天天看 | 激情A片久久久久久久 | 成人无码T髙潮喷水A片小说 | 欧美人成在线视频 | 中文字幕卡二和卡三的视频 | 香港三级日本三级三级韩级2 | 欧美日本免费一区二区三区 | 久久99久久99小草精品免视看 | www欧美| 一级片免费在线观看 | 高压监狱在线观看完整免费法剧 | 国产人妖在线视频 | 日韩一区二区视频在线观看 | 好久被狂躁A片视频无码免费视频 | 老头把我添高潮了A片故事 老王轻一点儿好爽在深一点 | 麻豆国产人妻欲求不满 | 中文字幕无限乱码不卡2021 | 国产黄A片免费网站免费 | 国产香蕉97碰碰久久人人 | 葫芦娃视频成人APP 蝴蝶谷成人 | 婷婷六月天激情 | 少爷湿润粗大跪趴含BL | 一区二区人妻无码欧美 | 黄桃AV无码免费一区二区三区 | 久久久麻豆 | 中文字幕不卡一区二区三区 | 欧美激情无码视频一二三 | 国产一国产一级毛片古装 | 国产激情艳情在线看视频 | 九色综合伊人久久富二代 | 中文字幕qvod | 99视频在线免费观看 | 亚洲综合在线最大成人 | 91免费国产精品 | 邻座的艾琳同学第一季 | 性做爰A片免费看网站 | 精品中文字幕一区在线 | 免费观看成人久久网免费观看 | 国产黄色在线免费观看 | 亚洲精品久久国产高清情趣 | 性色欲情网站IWWW九文堂 | 国产精品免费一级在线观看 | 彩途| 永久看免费bbbbb视频 | 久久久久久久久久久9精品视频 | 国产香线蕉手机视频在线观看 | 亚洲a在线视频 | 琪琪午夜福利免费院 | 色情综合另类小说图片 | 欧美日韩精品高清一区二区 | 国产免费午夜高清 | 一区二区三区影视 | 欧美一级免费在线观看 | 老司机午夜视频在线观看 | 国产三级日本三级在线播放 | 98色精品视频在线 | 欧美激情精品久久久久久久 | 亚洲国产欧美中文手机在线 | 婷婷五月五 | 国产电影在免费播放在线观看 | 少妇大叫太大太粗太爽了A片在线 | 长泽雅美av | 国产偷窥熟妇高潮呻吟 | 成年人视频免费网站 | 狠狠色噜噜狠狠狠狠色吗综合 | 国产AV精品一区二区三区小说 | 淫人色| 黑人性致| 中文字幕无线码国产 | 日本不卡一区二区三区 | 亚洲午夜久久久久影院 | 好大老师好爽快点深一点动漫 | 久久视频在线视频精品 | 97国产影院| 亚洲国产区男人本色在线观看 | 亚洲性生活视频 | 国产精品高清在线观看地址 | 欧美精品中文字幕亚洲专区 | 国家一级毛片 | 亚洲精品婷婷无码成人A片在线 | 成人国内精品久久久久影院 | 免费精品美女久久久久久久久 | 久久国产免费 | 久久免费国产视频 | 欧美色交| 亚洲精品鲁一鲁一区二区三区 | 久久亚洲精品AV无码四区 | 亚洲综合精品香蕉久久网97 | 国产SUV精二区69 | 伦理片在线观看午夜伦理电影三级网 | 尤物网站永久点击进入 | 亚洲欧美黄| 国产ts | 99视频精品国产免费观看 | 在线看黄色的网站 | 韩国轻色系电影 | 亚洲人午夜射精精品日韩 | 91精品久久久久久久久久 | 99热这里精品 | 一道本不卡免费高清在线 | 大香网伊人久久综合网2020 | 国产人妻一区二区三区色戒乐 | 日韩精品一区二区三区免费视频 | 欧洲免费在线视频 | 91久久国产综合精品 | 色网在线 | 国内自拍99P | 欧美在线视频二区 | 午夜www在线观看完整版视频 | 国产欧美精品一区二区色综合 | 国产又色又爽又黄又免费的小说 | 天天干天天爽天天操 | 色偷偷一区二区三区视频 | 深夜成人福利视频 | 亚洲成人午夜影院 | 亚洲视频日韩 | 九九国产精品视频 | 东京热主页| 亚洲一区二区免费视频 | 日日摸夜夜添夜夜添A片一Y | 国产伦理一区 | 88av在线视频 | 强奷皇后娇呻浪吟前后夹击 | jiizzyou欧美杂交18 | 日本一卡二卡三卡四卡试看 | 国产一区二区三区乱码 | 热门视频 | 色综合久久久久久888 | 色偷偷资源网 | 激情啪啪精品一区二区 | 亚洲精品在线免费 | 伦理电影在线 | 夜夜夜噜噜噜 | 免费无码又爽又黄又刺激网站 | 青青青国产在线观看手机免费 | 狠狠干狠狠干 | 国产免费区 | 日本无码黄人妻一区二区 | 久久亚洲精品玖玖玖玖 | 日本高清免费观看视频在线 | 日本一本二本三区免费免费高清 | 无码AV大香线蕉伊人久久 | 亚洲最大色情4338 | 亚洲午夜精品A片一区三区无码 | 最新中文字幕在线视频 | 欧美经典人人爽人人爽人人片 | 男人的天堂2024无码 | 久久精品久久久 | 国产a级精品特黄毛片 | 2024免费视频真人直播 | 污肉高H校园调教 | 中文字幕日本不卡 | 精品无码国产AV一区二区三区 | 色丁香综合 | 爆乳隔壁人妻中文字幕 | 第四色婷婷基地 | 欧美日韩综合一区 | 色欲AV亚洲永久无码精品 | 国产精品综合色区小说 | 久久久黄色大片 | 免费又黄又爽1000禁片 | 国产无套内射又大又猛又粗又爽 | 亚洲人成网亚洲欧洲无码 | 亚洲播播播 | 把女人弄爽大黄A大片片 | 中文字幕日本最新乱码视频 | 欧美激情无码成人A片 | 男女羞羞无遮掩视频免费网站 | 欧美日韩一卡2卡三卡4卡新区 | 第四色俺去也在线视频 | 国产精品永久免费自在线观看 | 午夜免费大片 | 中文字幕电影乱码在线观看 | 中文字幕一区二区三区在线不卡 | 一级毛片两人添下面 | 中文在线不卡 | 色婷婷综合在线 | 激情六月 | 校园黄乱色伦短篇小说 | 亚洲一级电影 | 日韩欧美三区 | 日韩小视频网站 | 日本在线无 | 中文字幕精品在线 | 一个色综合久久 | 三级理论中文字幕在线播放 | 好黄好猛好爽好痛的视频 | 亚洲国产精品色情777777 | 久久精品无码欧美成人一区 | 免费成人论坛 | 国产精品久久国产三级国不卡顿 | 国产美女被爽到高潮激情免费A片 | 精品黑人一区二区三区久久 | 免费一级a毛片 | 不卡高清AV手机在线观看 | 丰满熟妇啪啪区日韩久久 | 在线观看视频一区 | 欧美国产激情二区三区-免费A片 | 2020年最新国产精品正在播放 | 国产精品天天狠天天看 | 被少妇滋润了一夜爽爽爽小说 | 午夜视频福利在线观看 | 国产高清在线观看视频手机版 | 亚洲欧美国产日本 | 长篇YIN乱大合集TXT全文下载 | 四虎亚洲精品高清在线观看 | 在线色综合 | 色激情综合网 | 亚洲精品中文字幕无码A片老网站 | 被少妇滋润了一夜爽爽爽小说 | 天天天做天天天天爱天天想 | 国产成人久久综合第一区 | 国产精品女上位在线观看 | 香蕉久久一区二区三区啪啪 | 欧美hdxxx| 国产精品密蕾丝视频下载 | 日韩免费一区二区三区在线 | WW.2024色情网TUPIAN | 久久99精品国产99久久 | 91网站网址最新 | 偷拍快播 | 欧洲无人区卡一卡二卡三 | 黑人XOXO性欧美片 | www.日本com| 欧美一区二区三区四区在线观看 | 大菠萝app福引导welcome | 天天拍夜夜拍高清视频 | 免费爱爱片 | 日本加勒比视频在线观看 | 97国产在线视频 | 国产爱啪啪 | 综合激情婷婷 | 脱了在阳台趴着去H | 亚洲午夜无码久久久久蜜臀av | 久久久久久全都是精品app | 欧洲黄色毛片 | 农夫导航mcc| 免费看污又色又爽又黄又脏小说 | 免费国产黄网在线观看 | 帝王被大臣们调教高肉 | 高清无码专区av | 一个人看的www的视频免费 | 国产中的精品AV一区二区 | 五月天 亚洲 | 国产欧美久久久精品 | 一一电影院 | 主播蜜汁丝袜精品自拍 | 吉泽明步高清无码中文 | 日本免费一区二区三区视频 | 日韩国产精品99久久久久久 | 成 人 黄 色 免费网 | 午夜成年奭片免费观看 | 无码一区国产欧美在线资源 | 蝌蚪久久| 日韩高清在线观看永久 | 日本一区色情无码视频在线观看 | 日本a在线看 | 香港韩国三级日本三级 | 狼狼躁日日躁夜夜躁A片 | 被两个同桌绑起来玩乳动态gif | 免费看午夜高清性色生活片 | 国产精品国产三级国产AV麻豆 | 无码日本邻居大乳人妻波多野结衣 | JizzJizzJizz亚洲成年| 在线免费色视频 | 国产激情一区二区三区成人91 | 美国一级毛片免费 | 最近免费观看高清日本大全 | 久99久精品视频免费观看v | 亚洲精品国偷拍电影自产在线 | 国产精品99久久久久久AV小说 | 欧美xxxx做受欧美精品 | 国产日产欧产精品精品推荐在线 | 性一交一乱一A片 | 黄页网站在线观看视频 | www.黄色网.com | 邻座的艾琳同学第一季 | 这里只有精品6 | 成人网18免费软件大全 | 色窝窝华人社区 | 婷婷四月开心色房播播网 | 亚洲A片无码一区二区蜜桃久久 | 韩国三级日本三级香港三级黄 | 大菠萝福利污下载APP | 国产一区二区自拍视频 | 欧美性做爰又大又粗又长 | 欧洲午夜福利视频在线观看 | 激情欧美乱妇 | 国产hd高清freexxxx| 肉蒲团dvd| 日本免费观看的视频在线 | 色播欧美 | 草草视频免费在线观看 | 亚洲精品国产SUV | 日韩精品电影在线 | 亚洲 日韩 色 图网站 | 欧美变态杂交xxx | 玖玖精品在线视频 | 真人做爰到高潮A级 | 日本精品欧洲www | 亚洲AV无码区在线观看东京热 | 性色AV无码成人亚洲一区 | 品色堂 永久免费 | 国产日韩欧美精品一区二区三区 | 久久精品国产欧美日韩99热 | 国产亚洲日本精品无码电影 | 久久亚洲国产高清 | 在线精品国产一区二区 | 中文字幕 在线 欧美 日韩 制服 | 日本亚欧色情 | se94se最新网站| 青草娱乐| 波多野结衣三级在线观看 | 中国chinese国产高清 | 国产精品福利影院 | 久久精品视频在线直播6 | 激情五月婷婷在线 | 久久综合给合久久97色美利坚 | 亚洲精品一区二区在线看片 | 午夜福利麻豆国产精品 | 青青草视频成年视频在緌观看 | 免费观看美女被cao视频 | 免费无码一区二区三区蜜桃大 | 久久国产免费观看精品A片 久久国产免费观看精品1 | 天天插日日胔夜夜干 | 泷泽萝拉第一部快播 | a亚洲在线观看不卡高清 | 日本午夜精品久久久无码 | 日本三级黄线在线播放 | 波多野结衣免费 | 国产麻豆| 亚洲精品AV午夜一区二区三区 | 一级毛片免费在线观看网站 | 综合五月激情 | 最近中文字幕在线中文视频 | 色综合久| 国产激情久久久久影院小草 | 日产精品一区到六区免费 | 成人黄色一级片 | 免费在线观看的毛片 | 人妻少妇久久久久久97人妻 | 手机在线日本亚洲欧美视频 | 99色视频在线观看 | 久久天天综合 | 免费中文字幕不卡视频 | 国精产品三区四区有限公司 | 国产精品爽爽久久久久久无码 | 久久一本色道综合 | 男女啪啪永久免费观看网站 | 日本少妇裸体做爰高潮片 | 91免费视频播放 | 精品黑人一区二区三区久久 | 欧美又大又黄又粗又长A片 欧美又大又色又爽AAAA片 | 精品一区二区三区AV天堂 | 51人人看| 欧美精品视 | 男人一边吃奶一边做爰免费视频 | 日韩熟女精品一区二区三区 | 国产乱码精品一区二区三上 | 精品福利app导航 | 99精品成人无码A片观看金桔 | 日产一一到六区麻豆 | 各种场合肉H校园1V1 | 真人作爱视频免费视频大全 | 再深点舒服灬太大了添A片 在办公室里揉护士的胸 | 高清偷自拍第1页 | 日本无码一区人妻免费视频 | 又色又爽又高潮免费观看 | japanXXXXXXX日本| 先锋影音avt天堂影院 | 成人性视屏| 成熟交BGMBGMBGM在线看 | h网址在线 | 国产又粗又猛又爽的视频A片 | 波多野一区二区三区在线 | 日本在线观看视频网站 | 亚洲区欧美区 | 午夜精品久视频在线观看 | 在线播放91撕破艺校舞蹈系 | 女人十八毛片A片久久18 | 成人亚洲欧美日韩在线观看 | 国内精品乱码卡一卡2卡 | 国产AV亚洲AV麻豆专区 | 日韩免费黄色片 | 97蜜桃网站 | 国产三级精品在线 | 国产精品中文字幕在线 | 朱竹清把我夹得又紧又爽 | 性欧美精品videofree高清hd | 黄到下面流水的爽文很污的情话 | 亚洲精品深夜AV无码一区二区 | 91po国产在线精品免费观看 | 精品一区二区三区五区六区 | 日韩精品在线观看免费 | 成人综合国产乱在线 | 国产97人妻人人做人碰人人爽 | 让人爽到湿的小黄书软件下载 | 日本三级带日本三级带黄国产 | 四虎影视免费大全 | 欧美色欧美亚洲高清在线观看 | jizz日本| 日韩熟女精品一区二区三区 | 含紧一点H.边做边走教官 | 国产网曝在线观看视频 | 乱码一二三乱码又大又粗 | 色人阁26uuu 色情图插插插 | 欧美极品欧美日韩 | 97视频在线观看播放 | 在线播放一区 | 亚洲AV久久无码精品九九小说 | 让人爽到湿的小黄书软件下载 | 手机国产视频福利 | 免费精品国产人妻国语色戒 | 亚洲 欧美 小说 图片 视频 | 日本精品无码特级毛片 | 激情五月婷婷在线 | 国语电影 | 亚洲图片你懂得 | 国产精品久久久久毛片真精品 | 色在线网| 欧美在线视频网 | 3d动漫精品一区视频在线观看 | www.日本三级 | 亚洲精品中文一区二区在线 | 星野亚希 护士 | 国产福利小视频在线播放观看 | 亚洲综合日韩精品欧美综合区 | 乳交高H糙汉宠文 | 欧美性猛交一区二区三区精品 | 好爽快点我受不了了国产 | 国产偷国产偷亚州清高APP | 91视频com| 国产一区二区高清 | 伊人网综合在线 | 亚洲AV无码午夜国产精品色软件 | 精品国产三级在线观看 | 在线二区 | 激情四房 | 日本理论片强奷AA片 | 第四色 成人 官网 | 伊人久久大香线蕉无码麻豆 | 请以你的名字呼唤我 | 日本黄色网址大全 | 久久免费福利 | 边C边爱 | 久久精品中文字幕第一页 | 亚洲第6页 | 在线观看免费国产 | 色网快播 | 日本二区三区欧美亚洲国 | 色网站在线 | 麻豆最新国产剧情AV原创免费 | 美尻在线 | 久久国内精品视频 | 99精品久久久久久久免费看蜜月 | 久久免视频 | 欧美特黄99久久毛片免费 | 中文字幕视频在线播放 | 99re国产| 日本巨乳亚洲高清 | 福利免费观看午夜体检区 | 最美白嫩的极品美女ASSPICS | 国产亚洲精品久久久久婷婷瑜伽 | 日韩xxxx做受欧美 | 国产又爽又大又黄A片另类 国产又爽又大又黄A片软件 | 国产人妻人伦又粗又大爽歪歪 | 国产亚洲精品成人AA片 | 国产a不卡片精品免费观看 国产a不卡 | 日日摸天天摸97狠狠婷婷 | 天天操天天操天天干 | 波多野结衣torrent | 要狠狠撸 | 成人国产色情无码永久免费软件 | 国产不卡视频一区二区三区 | 诱人的女邻居在线观看 | 欧美精品18videose 性欧美 | 精品人妻无码一区二区三区手机板 | 性做爰AAA片免费看大尺度 | 日本精品人妻无码久久久 | 亚洲三级中文字幕 | 日本在线视频一区二区 | 天堂网在线看 | 亚洲性之站 | 99热只有 | 精品无人码麻豆乱码1区2区 | 亚洲国产精华液2024 | 偷偷撸2014最新版 | 9久热| 麻豆精品国产精华精华液好用吗 | 亚洲AV国产国产久青草 | 久久综合九色综合97免费下载 | 精品人妻无码一区二区三区蜜桃臀 | 久久厕所精品国产精品亚洲 | 啊灬啊灬啊灬快灬深用力A片 | 亚洲乱码国产乱码精华 | 永久视频在线观看 | 91精品手机国产在线观 | 色偷偷亚洲第一成人综合网址 | 欧美一级片免费观看 | 高清性色生活片免费播放网 | 九九视频精品全部免费播放 | 大尺度一级毛片波多野结衣 | 亚洲AV久久婷婷蜜臀无码不卡 | 国精产品一区一区三区 | 日本免费观看日本高清视频 | 成版人性视频app菠萝 | 国产极品美女视频福利 | 欧美一级夜夜爽 | 高清一区二区亚洲欧美日韩 | 国产福利你懂的 | 五月天婷婷视频在线观看 | 结衣波多野种子qvod | 久见久热 这里只有精品 | 天美传媒AV成人片免费看 | 97caopeng| 中文字幕不卡在线播放 | 婷婷色色狠狠爱 | 久久视频在线视频观看: | 成人性爱视频在线观看 | 黄色网址免费看 | 草草在线免费视频 | 青青青青青国产免费手机看视频 | 日本免费无码一区二区到五区 | 国产永久精品 | 好爽又高潮了毛片免费下载 | 瑟瑟网站免费网站入口 | 看一级毛片一区二区三区免费 | 黄色 在线| 麻豆高潮AV久久久久久久 | 爽死你个放荡粗暴小淫货h文 | 在线观看日本视频免费 | 人妻精品久久无码区新狼窝 | 久久久欧美国产精品人妻噜噜 | 欧美h片在线 | 日日噜噜夜夜狠狠 | 天天爽夜爽免费精品视频 | 黄视频网站观看 | 麻豆久久婷婷综合五月国产 | 久久久久免费 | 久久久久久久久影院 | 激情夜色 | 久久99精品一久久久久久 | 国产精品大尺度尺度视频 | 国产一级视频播放 | vodafone荷兰的app | 黄色成年网站 | 2019中文字幕在线 | 久久综合久久综合久久 | 亚洲高清无在码在线电影 | 中文字字幕在线中文乱码2019 | 最近最新中文字幕高清免费 | 最近的2024中文字幕国语版 小说 | 亚洲成人在线免费观看 | 武侠艳妇屈辱的张开双腿 | 久久尹人 | 狠狠躁天天躁 | 国产精品国产三级国产潘金莲 | 欧美午夜特黄AAAAAA片 |